EXPLORING THE CONTRIBUTION OF TLR7 TO SEX-BASED DISPARITIES IN RESPIRATORY SYNCYTIAL VIRUS (RSV)-INDUCED INFLAMMATION AND IMMUNITY

Exploring the Contribution of TLR7 to Sex-Based Disparities in Respiratory Syncytial Virus (RSV)-Induced Inflammation and Immunity

TLR7 plays a key role in Nightshirts recognizing viral RNA to initiate an immune response.Sex-based differences in the severity of RSV respiratory infections have been noted, and this may be related to higher expression of X-linked toll-like receptor 7 (TLR7) in female immune cells.Indeed, TLR7 has been shown to influence sex differences in respons

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Clinical effects of breast milk enema on meconium evacuation in premature infants: study protocol for a randomized controlled trial

Abstract Background Delayed meconium evacuation is an important cause of intestinal dysfunction in preterm infants.There are many methods to induce defecation in preterm infants: however, the effects are controversial.Finding a new intervention method to promote meconium evacuation in premature infants is necessary.Therefore, in the proposed study,

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Homoharringtonine demonstrates a cytotoxic effect against triple-negative breast cancer cell lines and acts synergistically with paclitaxel

Abstract The lack of targeted therapies for triple-negative breast cancer (TNBC) contributes to their high mortality rates and high risk of relapse compared to other subtypes of breast cancer.Most TNBCs (75%) have downregulated the expression of CREB3L1 (cAMP-responsive element binding protein 3 like 1), a transcription factor and metastasis suppre

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